This isn't about how clean your home is
These habits are just practical travel routine, the same as checking a smoke detector, not a reaction to anything having gone wrong.
At a hotel or rental
On arrival, a quick look at the mattress seams and headboard before unpacking takes a minute and is worth doing as routine. Keeping luggage on a rack or in the bathroom rather than directly on the bed or floor reduces the chance of anything transferring into your bags in the first place.
Packing to come home
Keeping worn clothing in a separate bag from clean items, and giving luggage a quick check before it comes back into the house, are both simple habits that reduce risk without being excessive about it.
Unpacking
Unpacking directly onto a hard floor rather than a bed, and washing and drying travel clothing promptly, are reasonable habits after any trip. None of this needs to become a source of anxiety. It's routine, not a response to a specific concern, unless something's actually been noticed.
Common questions
Do I need to do all of this after every trip?
These are reasonable habits, not requirements, do what feels practical for your routine.
I found something in my luggage after a trip, what now?
An inspection can confirm what you're dealing with before it's brought further into the home.
Are hotels more likely to have bed bugs than homes?
High guest turnover means more opportunity for introduction, which is why a quick check on arrival is a reasonable habit. It isn't a judgment on any particular property.